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  Data on immunogenicity and reactogenicity to COVID-19 vaccination among patients receiving maintenance dialysis

Karakizlis, H., Nahrgang, C., Strecker, K., Chen, J., Aly, M., Slanina, H., et al. (2022). Data on immunogenicity and reactogenicity to COVID-19 vaccination among patients receiving maintenance dialysis. DATA IN BRIEF, 42: 108271. doi:10.1016/j.dib.2022.108271.

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 Creators:
Karakizlis, Hristos, Author
Nahrgang, Christian, Author
Strecker, Kevin, Author
Chen, Jiangping, Author
Aly, Mostafa, Author
Slanina, Heiko, Author
Schuettler, Christian G., Author
Esso, Isla, Author
Wolter, Martin, Author
Todorova, Darina, Author
Jessen, Sonke, Author
Adamik, Andrea, Author
Ronco, Claudio, Author
Seeger, Werner1, Author              
Weimer, Rolf, Author
Sester, Martina, Author
Birk, Horst-Walter, Author
Husain-Syed, Faeq, Author
Affiliations:
1Lung Development and Remodeling, Max Planck Institute for Heart and Lung Research, Max Planck Society, ou_2591698              

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 Abstract: Compared with the general population, patients receiving maintenance dialysis are at increased risk for morbidity and mortality associated with coronavirus disease 2019 (COVID-19). Currently, data on severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2)-specific immunity post -vaccination in patients on maintenance dialysis are scarce given that the effectiveness of the vaccines has not been ex-plicitly tested in this population due to their common exclu-sion from SARS-CoV-2 vaccination trials. We herein present data of the specific cellular (interferon-gamma and interleukin-2 ELISpot assays) and humoral immune responses (dot plot array and chemiluminescent microparticle immunoassay) at 4 weeks and 6 weeks following a single dose or a com-plete homologous dual dose SARS-CoV-2 vaccine regimen in 60 adult patients on maintenance dialysis (six with a his-tory of COVID-19). The data was produced in a framework of a project focused on a) quantifying the immune response after full vaccination, b) evaluating the short-term durabil-ity of immune response, and c) examining the reactogenicity of SARS-CoV-2 vaccine regimens in patients on maintenance dialysis. (C) 2022 The Author(s). Published by Elsevier Inc.

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 Dates: 2022-05-16
 Publication Status: Published online
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 Rev. Type: -
 Identifiers: ISI: 000809227700016
DOI: 10.1016/j.dib.2022.108271
PMID: 35600839
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Title: DATA IN BRIEF
Source Genre: Journal
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Pages: - Volume / Issue: 42 Sequence Number: 108271 Start / End Page: - Identifier: ISSN: 2352-3409