ausblenden:
Schlagwörter:
short-term-memory
human corticospinal system
subthalamic nucleus stimulation
task-dependent modulation
human basal ganglia
parkinsons-disease
top-down
motor cortex
neuronal synchronization
phase synchronization
Zusammenfassung:
In this review, we consider the potential functional role of beta-band oscillations, which at present is not yet well understood. We discuss evidence from recent studies on top-down mechanisms involved in cognitive processing, on the motor system and on the pathophysiology of movement disorders that suggest a unifying hypothesis: beta-band activity seems related to the maintenance of the current sensorimotor or cognitive state. We hypothesize that beta oscillations and/or coupling in the beta-band are expressed more strongly if the maintenance of the status quo is intended or predicted, than if a change is expected. Moreover, we suggest that pathological enhancement of beta-band activity is likely to result in an abnormal persistence of the status quo and a deterioration of flexible behavioural and cognitive control.
