English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Freezing revisited: coordinated autonomic and central optimization of threat coping

Roelofs, K., & Dayan, P. (2022). Freezing revisited: coordinated autonomic and central optimization of threat coping. Nature Reviews Neuroscience, Epub ahead. doi:10.1038/s41583-022-00608-2.

Item is

Basic

show hide
Genre: Journal Article

Files

show Files

Locators

show
hide
Description:
-

Creators

show
hide
 Creators:
Roelofs, K, Author
Dayan, P1, Author              
Affiliations:
1Department of Computational Neuroscience, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_3017468              

Content

show
hide
Free keywords: -
 Abstract: Animals have sophisticated mechanisms for coping with danger. Freezing is a unique state that, upon threat detection, allows evidence to be gathered, response possibilities to be previsioned and preparations to be made for worst-case fight or flight. We propose that - rather than reflecting a passive fear state - the particular somatic and cognitive characteristics of freezing help to conceal overt responses, while optimizing sensory processing and action preparation. Critical for these functions are the neurotransmitters noradrenaline and acetylcholine, which modulate neural information processing and also control the sympathetic and parasympathetic branches of the autonomic nervous system. However, the interactions between autonomic systems and the brain during freezing, and the way in which they jointly coordinate responses, remain incompletely explored. We review the joint actions of these systems and offer a novel computational framework to describe their temporally harmonized integration. This reconceptualization of freezing has implications for its role in decision-making under threat and for psychopathology.

Details

show
hide
Language(s):
 Dates: 2022-06
 Publication Status: Published online
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.1038/s41583-022-00608-2
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Nature Reviews Neuroscience
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: England : Nature Publishing Group
Pages: - Volume / Issue: Epub ahead Sequence Number: - Start / End Page: - Identifier: ISSN: 1471-003X
CoNE: https://pure.mpg.de/cone/journals/resource/110985821000937