English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Strong selection and high mutation supply characterize experimental Chlorovirus evolution

Retel, C., Kowallik, V., Becks, L., & Feulner, P. G. D. (2022). Strong selection and high mutation supply characterize experimental Chlorovirus evolution. Virus Evolution, 8(1): veac003. doi:10.1093/ve/veac003.

Item is

Basic

show hide
Genre: Journal Article

Files

show Files
hide Files
:
veac003.pdf (Publisher version), 2MB
Name:
veac003.pdf
Description:
-
OA-Status:
Visibility:
Public
MIME-Type / Checksum:
application/pdf / [MD5]
Technical Metadata:
Copyright Date:
-
Copyright Info:
-

Locators

show

Creators

show
hide
 Creators:
Retel, Cas, Author
Kowallik, Vienna1, 2, Author           
Becks, Lutz1, 2, Author           
Feulner, Philine G. D.2, Author           
Affiliations:
1Emmy-Noether-Group Community Dynamics, Department Evolutionary Ecology (Milinski), Max Planck Institute for Evolutionary Biology, Max Planck Society, ou_2068285              
2External Organizations, ou_persistent22              

Content

show
hide
Free keywords: virus evolution; genomics; repeatable genomic change; predicted phenotypic effect; Chlorovirus PBCV-1.
 Abstract: Characterizing how viruses evolve expands our understanding of the underlying fundamental processes, such as mutation, selectionand drift. One group of viruses whose evolution has not yet been extensively studied is thePhycodnaviridae, a globally abundant familyof aquatic large double-stranded (ds) DNA viruses. Here we studied the evolutionary change ofParamecium bursariachlorella virus 1during experimental coevolution with its algal host. We used pooled genome sequencing of six independently evolved populations tocharacterize genomic change over five time points. Across six experimental replicates involving either strong or weak demographicfluctuations, we found single nucleotide polymorphisms (SNPs) at sixty-seven sites. The occurrence of genetic variants was highlyrepeatable, with just two of the SNPs found in only a single experimental replicate. Three genesA122/123R, A140/145RandA540Lshowed an excess of variable sites, providing new information about potential targets of selection duringChlorella–Chlorovirus coevo-lution. Our data indicated that the studied populations were not mutation-limited and experienced strong positive selection. Ourinvestigation highlighted relevant processes governing the evolution of aquatic large dsDNA viruses, which ultimately contributes to abetter understanding of the functioning of natural aquatic ecosystems.

Details

show
hide
Language(s): eng - English
 Dates: 2022-01-142021-08-272022-01-252022-01-252022-02
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.1093/ve/veac003
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Virus Evolution
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: UK : Oxford University Press
Pages: - Volume / Issue: 8 (1) Sequence Number: veac003 Start / End Page: - Identifier: Other: 2057-1577
CoNE: https://pure.mpg.de/cone/journals/resource/2057-1577