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  Complex small-molecule architectures regulate phenotypic plasticity in a nematode

Bose, N., Ogawa, A., von Reuss, S., Yim, J., Ragsdale, E., Sommer, R., et al. (2012). Complex small-molecule architectures regulate phenotypic plasticity in a nematode. Angewandte Chemie, International Edition in English, 51(50), 12438-12443. doi:10.1002/anie.201206797.

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Item Permalink: https://hdl.handle.net/21.11116/0000-000A-A8F8-1 Version Permalink: https://hdl.handle.net/21.11116/0000-000A-A8F9-0
Genre: Journal Article

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 Creators:
Bose, N, Author
Ogawa, A1, Author           
von Reuss, SH, Author
Yim, JJ, Author           
Ragsdale, EJ1, Author           
Sommer, RJ1, Author           
Schroeder, FC, Author
Affiliations:
1Department Integrative Evolutionary Biology, Max Planck Institute for Developmental Biology, Max Planck Society, ou_3375786              

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 Abstract: Chemistry the worm's way: The nematode Pristionchus pacificus constructs elaborate small molecules from modified building blocks of primary metabolism, including an unusual xylopyranose-based nucleoside (see scheme). These compounds act as signaling molecules to control adult phenotypic plasticity and dauer development and provide examples of modular generation of structural diversity in metazoans.

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 Dates: 2012-12
 Publication Status: Issued
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.1002/anie.201206797
PMID: 23161728
 Degree: -

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Title: Angewandte Chemie, International Edition in English
  Abbreviation : Angew. Chem., Int. Ed. Engl.
Source Genre: Journal
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Publ. Info: Weinheim : Wiley-VCH
Pages: - Volume / Issue: 51 (50) Sequence Number: - Start / End Page: 12438 - 12443 Identifier: ISSN: 0570-0833
CoNE: https://pure.mpg.de/cone/journals/resource/0570-0833