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Free keywords:
catalysis
deoxyribozymes
nucleic acids
origin of life
ribozymes
in-vitro evolution
lanthanide-dependent dnazyme
hairpin ribozyme
tetrahymena ribozyme
hammerhead ribozyme
base catalysis
transfer-rna
cleavage reaction
escherichia-coli
ribonucleic-acid
Chemistry
Abstract:
The cover feature illustrates various environmental factors influencing nucleic acid catalysis on early Earth, including temperature, pH, metal ion composition, dehydration and exposure to UV radiation. In order to explore plausible scenarios for early molecular evolution and to investigate the extent to which nucleic acid enzymes can adapt to non-physiological conditions, it is essential to understand how different environmental conditions both inhibit and potentiate nucleic acid catalysis. More information can be found in the Minireview by Kristian Le Vay, Hannes Mutschler et al.
