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  Dynamically regulating metabolic fluxes with synthetic metabolons

Zhang, Y., & Fernie, A. R. (2022). Dynamically regulating metabolic fluxes with synthetic metabolons. Trends in Biotechnology, 40(9), 1019-1020. doi:10.1016/j.tibtech.2022.06.005.

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Item Permalink: https://hdl.handle.net/21.11116/0000-000A-AD46-5 Version Permalink: https://hdl.handle.net/21.11116/0000-000C-2825-E
Genre: Journal Article

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 Creators:
Zhang, YJ1, Author           
Fernie, A. R.1, Author           
Affiliations:
1Central Metabolism, Department Willmitzer, Max Planck Institute of Molecular Plant Physiology, Max Planck Society, ou_1753339              

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Free keywords: auxin, CRISPR-Cas6, pathway flux, malate, substrate channeling, synthetic biology
 Abstract: Enzyme–enzyme assemblies commonly occur naturally, yet the factors that lead to their transient nature are not fully understood. Mitkas et al. have shown how clustered regularly interspaced short palindromic repeats (CRISPR) enzymes and RNA scaffolds allow synthetic enzyme complexes to be formed and disassembled as needed, providing powerful new tools for metabolic engineering.

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Language(s): eng - English
 Dates: 2022-06-222022-09
 Publication Status: Issued
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.1016/j.tibtech.2022.06.005
 Degree: -

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Title: Trends in Biotechnology
  Other : Trends Biotechnol.
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Amsterdam, Netherlands : Elsevier Current Trends
Pages: - Volume / Issue: 40 (9) Sequence Number: - Start / End Page: 1019 - 1020 Identifier: ISSN: 0167-7799
CoNE: https://pure.mpg.de/cone/journals/resource/110984180788411