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  The RATIOnal Role of Polyamines in Epidermal Differentiation

Allmeroth, K., & Denzel, M. (2021). The RATIOnal Role of Polyamines in Epidermal Differentiation. J Invest Dermatol, 141(9), 2105-2107. doi:10.1016/j.jid.2021.02.011.

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Item Permalink: https://hdl.handle.net/21.11116/0000-000A-F8D2-1 Version Permalink: https://hdl.handle.net/21.11116/0000-000A-F8D3-0
Genre: Journal Article

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https://www.ncbi.nlm.nih.gov/pubmed/34420674 (Any fulltext)
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 Creators:
Allmeroth, K.1, Author           
Denzel, M.1, Author           
Affiliations:
1Denzel – Metabolic and Genetic Regulation of Ageing, Research Groups, Max Planck Institute for Biology of Ageing, Max Planck Society, ou_3394008              

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 Abstract: Polyamines have been implicated in skin tumorigenesis; however, their role in epidermal homeostasis remains obscure. In a new article in the Journal of Investigative Dermatology, Rahim et al. (2021) report that keratinocyte differentiation requires a shift in polyamine ratios that is mediated by AMD1. Results suggest that targeting polyamine availability might be useful in the treatment of hyperproliferative skin disorders.

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 Dates: 2021-08-242021-08-24
 Publication Status: Issued
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 Identifiers: Other: 34420674
DOI: 10.1016/j.jid.2021.02.011
ISSN: 1523-1747 (Electronic)0022-202X (Linking)
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Title: J Invest Dermatol
Source Genre: Journal
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Pages: - Volume / Issue: 141 (9) Sequence Number: - Start / End Page: 2105 - 2107 Identifier: -