English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  No effects of prefrontal multichannel tACS at individual alpha frequency on phonological decisions

Werchowski, M., Stenner, T., Splittgerber, M., Siniatchkin, M., Nees, F., Hartwigsen, G., et al. (2022). No effects of prefrontal multichannel tACS at individual alpha frequency on phonological decisions. Clinical Neurophysiology, 142, 96-108. doi:10.1016/j.clinph.2022.07.494.

Item is

Basic

show hide
Genre: Journal Article

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Werchowski, Michael1, Author
Stenner, Tristan1, Author
Splittgerber, Meike1, Author
Siniatchkin, Michael1, 2, Author
Nees, Frauke1, Author
Hartwigsen, Gesa3, Author           
Moliadze, Vera1, Author
Affiliations:
1Institute of Medical Psychology and Medical Sociology, University Hospital of Schleswig-Holstein, Kiel, Germany, ou_persistent22              
2Clinic for Child and Adolescent Psychiatry and Psychotherapy, Medical Center Bethel, Bielefeld, Germany, ou_persistent22              
3Lise Meitner Research Group Cognition and Plasticity, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_3025665              

Content

show
hide
Free keywords: Alpha; Transcranial alternating current stimulation; Individual alpha frequency; Prefrontal cortex; Neurostimulation; Dyslexia
 Abstract: Objective Alpha oscillations are linked to inhibitory capabilities in higher cognitive processing. Transcranial alternating current stimulation (tACS) at 10 Hz can enhance alpha oscillations and modulate behaviour. One possibility to increase the efficacy of tACS may be stimulating at the individual alpha frequency (IAF). The present work addresses this issue (among others) to increase the current understanding of the functional role of alpha oscillations in higher cognitive tasks. Methods Twenty-two healthy and 13 dyslexic participants performed two word decision tasks while receiving IAF-tACS over the left prefrontal cortex. Resting EEG was recorded to detect electrophysiological changes. Cortical excitability was assessed with TMS. Results Dyslexic participants performed worse in the phonological task. However, no significant tACS effects were found. Interestingly, higher cortical excitability was correlated with faster responses in healthy controls. In dyslexics this association significantly differed in the phonological task. Conclusion The non-significant modulation by tACS might be explained by methodological limitations. Alternatively, it may indicate that alpha oscillations do not play a functional role in phonological decisions. The findings on cortical excitability expands the existing literature and may reflect the specific phonological deficit in dyslexics. Significance Our critical discussion of these null findings expands the systematic knowledge on alpha-tACS for future studies.

Details

show
hide
Language(s): eng - English
 Dates: 2022-07-172022-07-302022-10
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.1016/j.clinph.2022.07.494
Other: online ahead of print
PMID: 36029581
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Clinical Neurophysiology
  Other : Clin. Neurophysiol.
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Amsterdam : Elsevier
Pages: - Volume / Issue: 142 Sequence Number: - Start / End Page: 96 - 108 Identifier: ISSN: 1388-2457
CoNE: https://pure.mpg.de/cone/journals/resource/954926941726