English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Interplay of surface interaction and magnetic torque in single-cell motion of magnetotactic bacteria in microfluidic confinement

Codutti, A., Charsooghi, M., Cerdá Doñate, E., Taïeb, H. M., Robinson, T., Faivre, D., et al. (2022). Interplay of surface interaction and magnetic torque in single-cell motion of magnetotactic bacteria in microfluidic confinement. eLife, 11: eLife.71527. doi:10.7554/eLife.71527.

Item is

Basic

show hide
Genre: Journal Article

Files

show Files
hide Files
:
Article.pdf (Publisher version), 5MB
Name:
Article.pdf
Description:
-
OA-Status:
Gold
Visibility:
Public
MIME-Type / Checksum:
application/pdf / [MD5]
Technical Metadata:
Copyright Date:
-
Copyright Info:
-

Locators

show
hide
Locator:
primary data (Research data)
Description:
-
OA-Status:
Not specified

Creators

show
hide
 Creators:
Codutti, Agnese1, Author           
Charsooghi, Mohammad1, Author           
Cerdá Doñate, Elisa1, Author           
Taïeb, Hubert M.2, Author           
Robinson, Tom3, Author           
Faivre, Damien1, Author           
Klumpp, Stefan, Author
Affiliations:
1Damien Faivre, Biomaterialien, Max Planck Institute of Colloids and Interfaces, Max Planck Society, ou_1863290              
2Amaia Cipitria, Biomaterialien, Max Planck Institute of Colloids and Interfaces, Max Planck Society, ou_2489692              
3Tom Robinson, Theorie & Bio-Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society, ou_2288691              

Content

show
hide
Free keywords: -
 Abstract: Swimming microorganisms often experience complex environments in their natural habitat. The same is true for microswimmers in envisioned biomedical applications. The simple aqueous conditions typically studied in the lab differ strongly from those found in these environments and often exclude the effects of small volume confinement or the influence that external fields have on their motion. In this work, we investigate magnetically steerable microswimmers, specifically magnetotactic bacteria, in strong spatial confinement and under the influence of an external magnetic field. We trap single cells in micrometer-sized microfluidic chambers and track and analyze their motion, which shows a variety of different trajectories, depending on the chamber size and the strength of the magnetic field. Combining these experimental observations with simulations using a variant of an active Brownian particle model, we explain the variety of trajectories by the interplay between the wall interactions and the magnetic torque. We also analyze the pronounced cell-to-cell heterogeneity, which makes single-cell tracking essential for an understanding of the motility patterns. In this way, our work establishes a basis for the analysis and prediction of microswimmer motility in more complex environments.

Details

show
hide
Language(s): eng - English
 Dates: 2022-07-192022
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: eLife
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Cambridge : eLife Sciences Publications
Pages: - Volume / Issue: 11 Sequence Number: eLife.71527 Start / End Page: - Identifier: ISSN: 2050-084X

Source 2

show
hide
Title: bioRxiv
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Cold Spring Harbor, NY : Cold Spring Harbor Laboratory
Pages: - Volume / Issue: - Sequence Number: 2021.03.27.437322 Start / End Page: - Identifier: ZDB: 2766415-6