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  ReadClear: An assistive reading tool for people living with posterior cortical atrophy

Suarez-Gonzalez, A., Ocal, D., Pavisic, I., Peacock, A., Naessens, M., Ahmed, S., et al. (2019). ReadClear: An assistive reading tool for people living with posterior cortical atrophy. Journal of Alzheimer's Disease, 71(4), 1285-1295. doi:10.3233/JAD-190335.

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Datensatz-Permalink: https://hdl.handle.net/21.11116/0000-000B-131F-E Versions-Permalink: https://hdl.handle.net/21.11116/0000-000C-CEB7-E
Genre: Zeitschriftenartikel

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 Urheber:
Suarez-Gonzalez, Aida1, Autor
Ocal, Dilek1, 2, Autor           
Pavisic, Ivana1, 3, Autor
Peacock, Ashley1, Autor
Naessens, Michelle1, Autor
Ahmed, Samrah4, Autor
Butler, Christopher R.4, Autor
Leff, Alexander P.5, Autor
Yong, Keir X.X.1, Autor
Crutch, Sebastian J.1, Autor
Affiliations:
1Dementia Research Centre, Department of Neurodegenerative Disease, Institute of Neurology, University College London, United Kingdom, ou_persistent22              
2Department Neurophysics (Weiskopf), MPI for Human Cognitive and Brain Sciences, Max Planck Society, Leipzig, DE, ou_2205649              
3UK Dementia Research Institute, University College London, United Kingdom, ou_persistent22              
4Nuffield Department Clinical Neurosciences, FMRIB Centre, University of Oxford, United Kingdom, ou_persistent22              
5Department of Brain Repair & Rehabilitation, University College London, United Kingdom, ou_persistent22              

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Schlagwörter: Assistive technology; Dyslexia; Posterior cortical atrophy; Reading
 Zusammenfassung: Progressive reading impairment is an early and debilitating symptom of posterior cortical atrophy (PCA) arising from the progressive deterioration of visual processing skills. Objective: The goal of this study was to test the effectiveness of a purpose-built reading app (ReadClear) co-produced with people living with PCA and designed to reduce the reading difficulties experienced by this population (e.g., getting lost in the page and missing words when reading). Methods: Twenty subjects with PCA were included in a cross-over design home-based study aimed at determining whether ReadClear could 1) enhance the subjective reading experience (reading pleasantness) and 2) improve reading accuracy (reducing the number of reading errors) compared with a sham condition (a standard e-reader). Results: Reading using ReadClear provided a better subjective reading experience than sham (p=0.018, d=0.5) and significantly reduced the percentage of reading errors (p<0.0001, r=0.82), particularly errors due to omissions (p=0.01, r=0.50), repeated words (p=0.002, r=0.69), and regressions in the text (p=0.003, r=0.69). We found that different kinds of reading errors were related to specific neuropsychological profiles. Conclusion: ReadClear can assist reading in people living with PCA by reducing the number of reading errors and improving the subjective reading experience of users. © 2019 - IOS Press and the authors. All rights reserved.

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Sprache(n): eng - English
 Datum: 2019-08-072019-10-15
 Publikationsstatus: Erschienen
 Seiten: -
 Ort, Verlag, Ausgabe: -
 Inhaltsverzeichnis: -
 Art der Begutachtung: -
 Identifikatoren: DOI: 10.3233/JAD-190335
PMID: 31524161
 Art des Abschluß: -

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Projektname : -
Grant ID : -
Förderprogramm : -
Förderorganisation : Department of Health’s NIHR Biomedical Centres
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Förderprogramm : FP7/2007
Förderorganisation : European Commission (EC)
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Förderorganisation : Higher Education Funding Council for England
Projektname : -
Grant ID : MR/K010395/1
Förderprogramm : -
Förderorganisation : Medical Research Council (MRC)
Projektname : -
Grant ID : ES/L001810/1
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Förderorganisation : Economic and Social Research Council (ESRC)
Projektname : -
Grant ID : ES/K006711/1
Förderprogramm : -
Förderorganisation : National Institute for Health Research (NIHR)
Projektname : -
Grant ID : R337/0214
Förderprogramm : Dunhill Medical Trust (DMT)
Förderorganisation : -
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Grant ID : 616905
Förderprogramm : -
Förderorganisation : European Research Council (ERC)
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Grant ID : -
Förderprogramm : Alzheimer’s Research UK
Förderorganisation : -
Projektname : -
Grant ID : ARUK-NSG2017-4
Förderprogramm : -
Förderorganisation : NIHR Oxford Biomedical Research Centre (OxBRC)
Projektname : -
Grant ID : 453, AS-JF-18-003
Förderprogramm : -
Förderorganisation : Alzheimer’s Society
Projektname : -
Grant ID : -
Förderprogramm : Seventh Framework Programme
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Titel: Journal of Alzheimer's Disease
  Kurztitel : J. Alzheimers Dis.
Genre der Quelle: Zeitschrift
 Urheber:
Affiliations:
Ort, Verlag, Ausgabe: Amsterdam : IOS Press
Seiten: - Band / Heft: 71 (4) Artikelnummer: - Start- / Endseite: 1285 - 1295 Identifikator: ISSN: 1387-2877
CoNE: https://pure.mpg.de/cone/journals/resource/1387-2877