English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Synthetic approaches to break the chemical shift degeneracy of glycans

Dal Colle, M., Fittolani, G., & Delbianco, M. (2022). Synthetic approaches to break the chemical shift degeneracy of glycans. Chembiochem. doi:10.1002/cbic.202200416.

Item is

Files

show Files
hide Files
:
Article.pdf (Publisher version), 2MB
Name:
Article.pdf
Description:
-
OA-Status:
Not specified
Visibility:
Public
MIME-Type / Checksum:
application/pdf / [MD5]
Technical Metadata:
Copyright Date:
-
Copyright Info:
-

Locators

show

Creators

show
hide
 Creators:
Dal Colle, Marlene1, Author           
Fittolani, Giulio1, Author           
Delbianco, Martina1, Author           
Affiliations:
1Martina Delbianco, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society, ou_2559692              

Content

show
hide
Free keywords: glycans; NMR spectroscopy; isotopic labeling; protein-glycan interactions; site-specific labeling
 Abstract: NMR spectroscopy is the leading technique for determining glycans’ three-dimensional structure and dynamic in solution as well as a fundamental tool to study protein-glycan interactions. To overcome the severe chemical shift degeneracy of these compounds, synthetic probes carrying NMR-active nuclei (e.g., 13 C or 19 F) or lanthanide tags have been proposed. These elegant strategies permitted to simplify the complex NMR analysis of unlabeled analogues, shining light on glycans’ conformational aspects and interaction with proteins. Here, we highlight some key achievements in the synthesis of specifically labeled glycan probes and their contribution towards the fundamental understanding of glycans.

Details

show
hide
Language(s): eng - English
 Dates: 2022-08-25
 Publication Status: Published online
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.1002/cbic.202200416
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Chembiochem
  Other : Chembiochem
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Weinheim, Germany : Wiley-VCH
Pages: - Volume / Issue: - Sequence Number: - Start / End Page: - Identifier: ISSN: 1439-4227