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  STEAM-DWI as a robust alternative to EPI-DWI: Evaluation in pediatric brain MRI

Gräfe, D., Päts, A., Merkenschlager, A., Roth, C., Hirsch, F. W., Frahm, J., et al. (2022). STEAM-DWI as a robust alternative to EPI-DWI: Evaluation in pediatric brain MRI. PLoS One, 17(5): e0268523. doi:doi.org/10.1371/journal.pone.0268523.

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Gräfe, D., Autor
Päts, A., Autor
Merkenschlager, A., Autor
Roth, C., Autor
Hirsch, F. W., Autor
Frahm, J.1, Autor           
Voit, D.1, Autor
Affiliations:
1Research Group Biomedical NMR, Max Planck Institute for Multidisciplinary Sciences, Max Planck Society, ou_3350294              

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 Zusammenfassung: Purpose

Diffusion-weighted imaging (DWI) is an essential element of almost every brain MRI examination. The most widely applied DWI technique, a single-shot echo-planar imaging DWI (EPI-DWI) sequence, suffers from a high sensitivity to magnetic field inhomogeneities. As an alternative, a single-shot stimulated echo acquisition mode diffusion-weighted MRI (STEAM-DWI) has recently been re-introduced after it became significantly faster. The aim of the study was to investigate the applicability of STEAM-DWI as a substitute to EPI-DWI in a daily routine of pediatric radiology.

Methods

Retrospectively, brain MRI examinations of 208 children with both EPI-DWI and STEAM-DWI were assessed. Visual resolution and diagnostic confidence were evaluated, the extent of susceptibility artifacts was quantified, and contrast-to-noise ratio was calculated in case of diffusion restriction. Furthermore, the correlation of apparent diffusion coefficient values between STEAM-DWI and EPI-DWI was tested.

Results

STEAM-DWI was inferior to EPI-DWI in visual resolution but with higher diagnostic confidence and lower artifact size. The apparent diffusion coefficient values of both sequences demonstrated excellent correlation. The contrast-to-noise ratio of STEAM-DWI was only half of that of EPI-DWI (58% resp. 112%).

Conclusion

STEAM-DWI is a robust alternative to EPI-DWI when increased susceptibility artifacts are to be expected. Drawbacks are a lower contrast-to-noise ratio and poorer visual resolution.

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Sprache(n): eng - English
 Datum: 2021-12-222022-05-022022-05-18
 Publikationsstatus: Online veröffentlicht
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 Art der Begutachtung: Expertenbegutachtung
 Identifikatoren: DOI: doi.org/10.1371/journal.pone.0268523
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Titel: PLoS One
  Kurztitel : PLoS One
Genre der Quelle: Zeitschrift
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Affiliations:
Ort, Verlag, Ausgabe: San Francisco, CA : Public Library of Science
Seiten: - Band / Heft: 17 (5) Artikelnummer: e0268523 Start- / Endseite: - Identifikator: ISSN: 1932-6203
CoNE: https://pure.mpg.de/cone/journals/resource/1000000000277850