English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  The complete sequence of a human genome.

Nurk, S., Koren, S., Rhie, A., Rautiainen, M., Bzikadze, A. V., Mikheenko, A., et al. (2022). The complete sequence of a human genome. Science (New York, N.Y.), 376(6588), 44-53. doi:10.1126/science.abj6987.

Item is

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Nurk, Sergey, Author
Koren, Sergey, Author
Rhie, Arang, Author
Rautiainen, Mikko, Author
Bzikadze, Andrey V, Author
Mikheenko, Alla, Author
Vollger, Mitchell R, Author
Altemose, Nicolas, Author
Uralsky, Lev, Author
Gershman, Ariel, Author
Aganezov, Sergey, Author
Hoyt, Savannah J, Author
Diekhans, Mark, Author
Logsdon, Glennis A, Author
Alonge, Michael, Author
Antonarakis, Stylianos E, Author
Borchers, Matthew, Author
Bouffard, Gerard G, Author
Brooks, Shelise Y, Author
Caldas, Gina V, Author
Chen, Nae-Chyun, AuthorCheng, Haoyu, AuthorChin, Chen-Shan, AuthorChow, William, AuthorLima, Leonardo G de, AuthorDishuck, Philip C, AuthorDurbin, Richard, AuthorDvorkina, Tatiana, AuthorFiddes, Ian T, AuthorFormenti, Giulio, AuthorFulton, Robert S, AuthorFungtammasan, Arkarachai, AuthorGarrison, Erik, AuthorGrady, Patrick G S, AuthorGraves-Lindsay, Tina A, AuthorHall, Ira M, AuthorHansen, Nancy F, AuthorHartley, Gabrielle A, AuthorHaukness, Marina, AuthorHowe, Kerstin, AuthorHunkapiller, Michael W, AuthorJain, Chirag, AuthorJain, Miten, AuthorJarvis, Erich D, AuthorKerpedjiev, Peter, AuthorKirsche, Melanie, AuthorKolmogorov, Mikhail, AuthorKorlach, Jonas, AuthorKremitzki, Milinn, AuthorLi, Heng, AuthorMaduro, Valerie V, AuthorMarschall, Tobias, AuthorMcCartney, Ann M, AuthorMcDaniel, J, AuthorMiller, Danny E, AuthorMullikin, James C, AuthorMyers, Eugene W1, Author           Olson, Nathan D, AuthorPaten, Benedict, AuthorPeluso, Paul, AuthorPevzner, Pavel, AuthorPorubsky, David, AuthorPotapova, Tamara, AuthorRogaev, Evgeny I, AuthorRosenfeld, Jeffrey A, AuthorSalzberg, Steven L, AuthorSchneider, Valerie A, AuthorSedlazeck, Fritz J, AuthorShafin, Kishwar, AuthorShew, Colin J, AuthorShumate, Alaina, AuthorSims, Ying, AuthorSmit, Arian F A, AuthorSoto, Daniela C, AuthorSović, Ivan, AuthorStorer, Jessica M, AuthorStreets, Aaron, AuthorSullivan, Beth A, AuthorThibaud-Nissen, Francoise, AuthorTorrance, James, AuthorWagner, Justin, AuthorWalenz, Brian, AuthorWenger, Aaron M, AuthorWood, Jonathan, AuthorXiao, Chunlin, AuthorYan, Stephanie M, AuthorYoung, Alice C, AuthorZarate, Samantha, AuthorSurti, Urvashi, AuthorMcCoy, Rajiv C, AuthorDennis, Megan Y, AuthorAlexandrov, Ivan A, AuthorGerton, Jennifer L, AuthorO'Neill, Rachel J, AuthorTimp, Winston, AuthorZook, Justin M, AuthorSchatz, Michael C, AuthorEichler, Evan E, AuthorMiga, Karen H, AuthorPhillippy, Adam M, Author more..
Affiliations:
1Max Planck Institute for Molecular Cell Biology and Genetics, Max Planck Society, ou_2340692              

Content

show
hide
Free keywords: -
 Abstract: Since its initial release in 2000, the human reference genome has covered only the euchromatic fraction of the genome, leaving important heterochromatic regions unfinished. Addressing the remaining 8% of the genome, the Telomere-to-Telomere (T2T) Consortium presents a complete 3.055 billion-base pair sequence of a human genome, T2T-CHM13, that includes gapless assemblies for all chromosomes except Y, corrects errors in the prior references, and introduces nearly 200 million base pairs of sequence containing 1956 gene predictions, 99 of which are predicted to be protein coding. The completed regions include all centromeric satellite arrays, recent segmental duplications, and the short arms of all five acrocentric chromosomes, unlocking these complex regions of the genome to variational and functional studies.

Details

show
hide
Language(s):
 Dates: 2022-04-01
 Publication Status: Issued
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.1126/science.abj6987
Other: cbg-8333
PMID: 35357919
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Science (New York, N.Y.)
  Other : Science
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: 376 (6588) Sequence Number: - Start / End Page: 44 - 53 Identifier: -