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Free keywords:
Tourette Syndrome, MRI, PET, qMRI, MRS, Susceptibility, Multimodal, Dopamine, D1 receptors, Iron
Abstract:
We use multimodal Imaging (MRSI-PET) to characterize the metabolic alterations in patients with Tourette Syndrome. For first time the D1 Dopamine receptors density is assessed through PET, GABA, Glu and Gln through MRS and last, the power of 7T Scanners is employed through qMRI (QSM) to assess potential local abnormalities in the brain iron distribution of the GTS patient Vs the controls group.