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  Depth of focus extension in optical coherence tomography using ultrahigh chromatic dispersion of zinc selenide

Romodina, M. N., & Singh, K. (2022). Depth of focus extension in optical coherence tomography using ultrahigh chromatic dispersion of zinc selenide. Journal of Biophotonics, 15(8): e202200051. doi:10.1002/jbio.202200051.

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This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. © 2022 The Authors. Journal of Biophotonics published by Wiley-VCH GmbH.

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 Creators:
Romodina, Maria N.1, Author           
Singh, Kanwarpal1, 2, 3, Author           
Affiliations:
1Singh Research Group, Research Groups, Max Planck Institute for the Science of Light, Max Planck Society, ou_3164411              
2Max-Planck-Zentrum für Physik und Medizin, Max Planck Institute for the Science of Light, Max Planck Society, ou_3164414              
3Department of Physics, Friedrich Alexander University Erlangen-Nürnberg, Erlangen, Germany, ou_persistent22              

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Free keywords: chromatic dispersion, cornea tissue, depth of focus, fat tissue, imaging, optical coherence tomography
 Abstract: We report a novel technique to overcome the depth-of-focus limitation in optical coherence tomography (OCT) using chromatic dispersion of zinc selenide lens. OCT is an established method of optical imaging, which found numerous biomedical applications. However, the depth scanning range of high-resolution OCT is limited by its depth of focus. Chromatic dispersion of zinc selenide lens allows to get high lateral resolution along extended depth of focus, because the different spectral components are focused at a different position along axes of light propagation. Test measurements with nanoparticle phantom show 2.8 times extension of the depth of focus compare to the system with a standard achromatic lens. The feasibility of biomedical applications was demonstrated by ex vivo imaging of the pig cornea and chicken fat tissue.

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Language(s): eng - English
 Dates: 2022-05-13
 Publication Status: Issued
 Pages: -
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 Identifiers: DOI: 10.1002/jbio.202200051
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Title: Journal of Biophotonics
Source Genre: Journal
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Publ. Info: Wiley VCH
Pages: - Volume / Issue: 15 (8) Sequence Number: e202200051 Start / End Page: - Identifier: -