Does one size fit all? Reconstructing crossing fibers in diffusion MRI using 
spherical deconvolution with local response functions

Eichner, Cornelius; Paquette, Michael; Gerbeth, Hannah; Jäger, Carsten; Bock, Christian; Gallardo, Guillermo; Möller, Torsten; Crockford, Catherine; Wittig, Roman; Weiskopf, Nikolaus; Friederici, Angela D.; Anwander, Alfred

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Does one size fit all? Reconstructing crossing fibers in diffusion MRI using spherical deconvolution with local response functions

Eichner, C., Paquette, M., Gerbeth, H., Jäger, C., Bock, C., Gallardo, G., et al. (2022). Does one size fit all? Reconstructing crossing fibers in diffusion MRI using spherical deconvolution with local response functions. Poster presented at 31st Annual Meeting of the International Society for Magnetic Resonance in Medicine (ISMRM), London, United Kingdom.

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Item Permalink: https://hdl.handle.net/21.11116/0000-000B-409F-A Version Permalink: https://hdl.handle.net/21.11116/0000-000B-9ACF-F

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https://index.mirasmart.com/ISMRM2022/PDFfiles/0877.html (Any fulltext) Open Access status unknown

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Creators:
Eichner, Cornelius¹, Author
Paquette, Michael¹, Author
Gerbeth, Hannah¹, Author
Jäger, Carsten², Author
Bock, Christian, Author
Gallardo, Guillermo¹, Author
Möller, Torsten, Author
Crockford, Catherine, Author
Wittig, Roman, Author
Weiskopf, Nikolaus², Author
Friederici, Angela D.¹, Author
Anwander, Alfred¹, Author

Affiliations:
1Department Neuropsychology, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634551
2Department Neurophysics (Weiskopf), MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_2205649

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Abstract: We present Local Spherical Deconvolution (LSD), a diffusion MRI deconvolution method to reconstruct crossing fiber directions in the brain. In contrast to previous approaches which assumed a single deconvolution kernel for the entire brain, LSD utilizes information theory to identify an optimal kernel in each image voxel. Using a high-resolution post-mortem chimpanzee brain, we show that fibers are reconstructed with LSD with increased precision and a reduced number of false peaks compared to conventional methods. A test-retest analysis supports the stability and accuracy of LSD.

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Dates: Created: 2022-05-07

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Title: 31st Annual Meeting of the International Society for Magnetic Resonance in Medicine (ISMRM)

Place of Event: London, United Kingdom

Start-/End Date: 2022-05-07 - 2022-05-12

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