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  Does one size fit all? Reconstructing crossing fibers in diffusion MRI using spherical deconvolution with local response functions

Eichner, C., Paquette, M., Gerbeth, H., Jäger, C., Bock, C., Gallardo, G., et al. (2022). Does one size fit all? Reconstructing crossing fibers in diffusion MRI using spherical deconvolution with local response functions. Poster presented at 31st Annual Meeting of the International Society for Magnetic Resonance in Medicine (ISMRM), London, United Kingdom.

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https://index.mirasmart.com/ISMRM2022/PDFfiles/0877.html (beliebiger Volltext)
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 Urheber:
Eichner, Cornelius1, Autor                 
Paquette, Michael1, Autor                 
Gerbeth, Hannah1, Autor
Jäger, Carsten2, Autor
Bock, Christian, Autor
Gallardo, Guillermo1, Autor                 
Möller, Torsten, Autor
Crockford, Catherine, Autor
Wittig, Roman, Autor
Weiskopf, Nikolaus2, Autor                 
Friederici, Angela D.1, Autor                 
Anwander, Alfred1, Autor                 
Affiliations:
1Department Neuropsychology, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634551              
2Department Neurophysics (Weiskopf), MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_2205649              

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 Zusammenfassung: We present Local Spherical Deconvolution (LSD), a diffusion MRI deconvolution method to reconstruct crossing fiber directions in the brain. In contrast to previous approaches which assumed a single deconvolution kernel for the entire brain, LSD utilizes information theory to identify an optimal kernel in each image voxel. Using a high-resolution post-mortem chimpanzee brain, we show that fibers are reconstructed with LSD with increased precision and a reduced number of false peaks compared to conventional methods. A test-retest analysis supports the stability and accuracy of LSD.

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 Datum: 2022-05-07
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Veranstaltung

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Titel: 31st Annual Meeting of the International Society for Magnetic Resonance in Medicine (ISMRM)
Veranstaltungsort: London, United Kingdom
Start-/Enddatum: 2022-05-07 - 2022-05-12

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