English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
Add to Basket
 Local TagsRelease HistoryDetailsSummary
  Localization matters in targeted protein degradation

Shah, V. J., & Đikić, I. (2022). Localization matters in targeted protein degradation. Cell Chemical Biology, 29(10), 1465-1466. doi:10.1016/j.chembiol.2022.09.006.

Item is

 

show all hide all

Basic

show hide
Item Permalink: https://hdl.handle.net/21.11116/0000-000B-528B-C Version Permalink: https://hdl.handle.net/21.11116/0000-000C-16F8-4
Genre: Journal Article

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Shah, Varun Jayeshkumar1, Author
Đikić, Ivan1, 2, 3, 4, Author                 
Affiliations:
1Institute of Biochemistry II, Faculty of Medicine, Goethe University, Frankfurt, Germany, ou_persistent22              
2Buchmann Institute for Molecular Life Sciences, Goethe University, Frankfurt, Germany, ou_persistent22              
3Max Planck Fellow Group ER remodelling Group, Prof. Ivan Đikić, Max Planck Institute of Biophysics, Max Planck Society, ou_3004983              
4Fraunhofer Institute for Molecular Biology and Applied Ecology (IME), Branch Translational Medicine and Pharmacology, Frankfurt, Germany, ou_persistent22              

Content

show
hide
Free keywords: -
 Abstract: Many factors influence the efficiency of targeted protein degradation induced by proteolysis targeting chimeras (PROTACs). In this issue of Cell Chemical Biology, Simpson et al. (2022) highlight the impact of subcellular localization. Their study elucidates that the protein of interest exhibits different amenability to PROTAC-mediated degradation at different cellular compartments.

Details

show
hide
Language(s): eng - English
 Dates: 2022-10-20
 Publication Status: Published online
 Pages: 2
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1016/j.chembiol.2022.09.006
BibTex Citekey: shah_localization_2022
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Cell Chemical Biology
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Cell Press
Pages: - Volume / Issue: 29 (10) Sequence Number: - Start / End Page: 1465 - 1466 Identifier: ISSN: 2451-9456
CoNE: https://pure.mpg.de/cone/journals/resource/2451-9456