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  Scaling brain size, keeping timing: Evolutionary preservation of brain rhythms

Buzsáki, G., Logothetis, N., & Singer, W. (2013). Scaling brain size, keeping timing: Evolutionary preservation of brain rhythms. Neuron, 80(3), 751-764. doi:10.1016/j.neuron.2013.10.002.

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Buzsaki_2013_ScalingBrainSize.pdf (Publisher version), 2MB
 
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2013
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Copyright © 2013 Elsevier Inc.
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 Creators:
Buzsáki, György, Author
Logothetis, Nikos, Author
Singer, Wolf1, 2, Author                 
Affiliations:
1Ernst Strüngmann Institute (ESI) for Neuroscience in Cooperation with Max Planck Society, Max Planck Society, ou_2074314              
2Singer Lab, Ernst Strüngmann Institute (ESI) for Neuroscience in Cooperation with Max Planck Society, Max Planck Society, Deutschordenstraße 46, 60528 Frankfurt, DE, ou_3381220              

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Free keywords: cat visual-cortex hippocampal theta-oscillations gamma-oscillations in-vivo neuronal oscillations high-frequency human sleep electroencephalogram eeg phase synchronization neocortical neurons
 Abstract: Despite the several-thousand-fold increase of brain volume during the course of mammalian evolution, the hierarchy of brain oscillations remains remarkably preserved, allowing for multiple-time-scale communication within and across neuronal networks at approximately the same speed, irrespective of brain size. Deployment of large-diameter axons of long-range neurons could be a key factor in the preserved time management in growing brains. We discuss the consequences of such preserved network constellation in mental disease, drug discovery, and interventional therapies.

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 Dates: 2013
 Publication Status: Issued
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 Rev. Type: Peer
 Identifiers: DOI: 10.1016/j.neuron.2013.10.002
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Title: Neuron
Source Genre: Journal
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Pages: - Volume / Issue: 80 (3) Sequence Number: - Start / End Page: 751 - 764 Identifier: ISSN: 08966273