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Schlagwörter:
Animals
Longevity/*physiology
Neurons, Afferent/physiology
Olfactory Receptor Neurons/*physiology
Taste/*physiology
Zusammenfassung:
Insulin/IGF signaling has emerged as a central regulator of metazoan aging. In C. elegans, insulin-like peptides are expressed predominately in neurons. Alcedo and Kenyon demonstrate that removal of specific gustatory and olfactory neurons result in longer life, suggesting that metazoan longevity is influenced by sensory perception.