非表示:
キーワード:
Adaptation, Physiological
Animals
Caenorhabditis elegans/*chemistry/*physiology
Pheromones/chemistry/physiology
Signal Transduction
要旨:
In C. elegans, dauer pheromone is an indicator of population density and influences pathways that regulate metabolism, development, and aging. In a recent publication in Nature, Paik and coworkers (Jeong at al., 2005) show the purified substance to be a pyran ring conjugated to heptanoic acid, setting the stage for dissecting downstream signaling pathways.