非表示:
キーワード:
Adaptation, Physiological
Aging/*metabolism
Animals
Biotransformation
Caloric Restriction
Dose-Response Relationship, Drug
Environmental Pollutants/*pharmacology/toxicity
Humans
Insulin/metabolism
Insulin-Like Growth Factor I/metabolism
Longevity/*drug effects
Signal Transduction/*drug effects
Stress, Physiological/chemically induced/*metabolism/physiopathology
要旨:
Hormesis refers to the beneficial effects of a treatment that at a higher intensity is harmful. In one form of hormesis, sublethal exposure to stressors induces a response that results in stress resistance. The principle of stress-response hormesis is increasingly finding application in studies of aging, where hormetic increases in life span have been seen in several animal models.
