Deutsch
 
Hilfe Datenschutzhinweis Impressum
  DetailsucheBrowse

Datensatz

 
 
DownloadE-Mail
  Mitochondrial Dynamics and Metabolic Regulation

Wai, T., & Langer, T. (2016). Mitochondrial Dynamics and Metabolic Regulation. Trends Endocrinol Metab, 27(2), 105-17. doi:10.1016/j.tem.2015.12.001.

Item is

Basisdaten

einblenden: ausblenden:
Genre: Zeitschriftenartikel

Externe Referenzen

einblenden:
ausblenden:
externe Referenz:
https://www.ncbi.nlm.nih.gov/pubmed/26754340 (beliebiger Volltext)
Beschreibung:
-
OA-Status:
Keine Angabe

Urheber

einblenden:
ausblenden:
 Urheber:
Wai, T., Autor
Langer, T.1, Autor           
Affiliations:
1Department Langer - Mitochondrial Proteostasis, Max Planck Institute for Biology of Ageing, Max Planck Society, ou_3393994              

Inhalt

einblenden:
ausblenden:
Schlagwörter: Animals Humans Mitochondria/*metabolism Mitochondrial Dynamics/*physiology Mitochondrial Membranes/metabolism Oxidative Phosphorylation Protein Processing, Post-Translational Stress, Physiological Unfolded Protein Response/physiology fission fusion metabolism mitochondria mitochondrial dynamics
 Zusammenfassung: Mitochondrial morphology varies tremendously across cell types and tissues, changing rapidly in response to external insults and metabolic cues, such as nutrient status. The many functions of mitochondria have been intimately linked to their morphology, which is shaped by ongoing events of fusion and fission of outer and inner membranes (OM and IM). Unopposed fission causes mitochondrial fragmentation, which is generally associated with metabolic dysfunction and disease. Unopposed fusion results in a hyperfused network and serves to counteract metabolic insults, preserve cellular integrity, and protect against autophagy. Here, we review the ways in which metabolic alterations convey changes in mitochondrial morphology and how disruption of mitochondrial morphology impacts cellular and organismal metabolism.

Details

einblenden:
ausblenden:
Sprache(n):
 Datum: 2016-022016-01-13
 Publikationsstatus: Erschienen
 Seiten: -
 Ort, Verlag, Ausgabe: -
 Inhaltsverzeichnis: -
 Art der Begutachtung: -
 Identifikatoren: Anderer: 26754340
DOI: 10.1016/j.tem.2015.12.001
ISSN: 1879-3061 (Electronic)1043-2760 (Linking)
 Art des Abschluß: -

Veranstaltung

einblenden:

Entscheidung

einblenden:

Projektinformation

einblenden:

Quelle 1

einblenden:
ausblenden:
Titel: Trends Endocrinol Metab
Genre der Quelle: Zeitschrift
 Urheber:
Affiliations:
Ort, Verlag, Ausgabe: -
Seiten: - Band / Heft: 27 (2) Artikelnummer: - Start- / Endseite: 105 - 17 Identifikator: -