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  Enabling technologies in carbohydrate chemistry : automated glycan assembly, flow chemistry and data science

Lin, M.-H., Wolf, J., Sletten, E. T., Cambié, D., Danglad-Flores, J. A., & Seeberger, P. H. (2023). Enabling technologies in carbohydrate chemistry: automated glycan assembly, flow chemistry and data science. Chembiochem, 24(4): e202200607. doi:10.1002/cbic.202200607.

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 Creators:
Lin, Mei-Huei1, Author           
Wolf, Jakob2, Author           
Sletten, Eric T.1, Author           
Cambié, Dario2, Author                 
Danglad-Flores, José Angél1, Author                 
Seeberger, Peter H.1, Author                 
Affiliations:
1Peter H. Seeberger - Automated Systems, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society, ou_1863306              
2Dario Cambié, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society, ou_3256668              

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Free keywords: Carbohydrates; Glycosylation; Oligosachharides; Reaction automation; Flow chemistry
 Abstract: The synthesis of defined oligosaccharides is a complex task. Several enabling technologies have been introduced in the last two decades to facilitate synthetic access to these valuable biomolecules. In this concept, we describe the technological solutions that have advanced glycochemistry using automated glycan assembly, flow chemistry and data science as examples. We highlight how the synergies between these different technologies can further advance the field, with progress toward the realization of a self-driving lab for glycan synthesis.

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Language(s): eng - English
 Dates: 2022-11-162023
 Publication Status: Issued
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 Table of Contents: -
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 Identifiers: DOI: 10.1002/cbic.202200607
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Title: Chembiochem
  Other : Chembiochem
Source Genre: Journal
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Publ. Info: Weinheim, Germany : Wiley-VCH
Pages: - Volume / Issue: 24 (4) Sequence Number: e202200607 Start / End Page: - Identifier: ISSN: 1439-4227