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  Zebrafish cell clocks feel the heat and see the light!

Vallone, D., Lahiri, K., Dickmeis, T., & Foulkes, N. (2005). Zebrafish cell clocks feel the heat and see the light! Zebrafish, 2(3), 171-187. doi:10.1089/zeb.2005.2.171.

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Vallone, D1, Author                 
Lahiri, K1, Author           
Dickmeis, T1, Author                 
Foulkes, NS1, Author                 
Affiliations:
1Research Group Zebrafish Chronobiology, Max Planck Institute for Developmental Biology, Max Planck Society, ou_3391226              

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 Abstract: The zebrafish has rapidly become established as one of the most valuable vertebrate models for studying circadian clock function. A major initial attraction was its utility in large-scale genetic screens. It subsequently emerged that most zebrafish cells possess circadian clocks that can be entrained directly by exposure to temperature or light dark cycles, a property shared by several zebrafish cell lines. This is not the case for mammals, where the retina is the primary source of light input to the clock. Furthermore, mammalian cell culture clocks can only be entrained by acute culture treatments such as serum shocks. Thus, the zebrafish is proving invaluable to study light and temperature input to the vertebrate clock. In addition, the accessibility of its early developmental stages has placed the zebrafish at the forefront of studies aimed at understanding how the circadian clock is established during embryogenesis.

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 Dates: 2005-12
 Publication Status: Published in print
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 Rev. Type: -
 Identifiers: DOI: 10.1089/zeb.2005.2.171
PMID: 18248192
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Title: Zebrafish
Source Genre: Journal
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Publ. Info: Larchmont, NY, USA : Liebert
Pages: - Volume / Issue: 2 (3) Sequence Number: - Start / End Page: 171 - 187 Identifier: ISSN: 1545-8547
CoNE: https://pure.mpg.de/cone/journals/resource/1545-8547