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  AAA ATPases

Martin, J. (2021). AAA ATPases. In J. Jez (Ed.), Encyclopedia of Biological Chemistry (3. ed., pp. 513-523). San Diego, CA, USA: Elsevier.

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 Urheber:
Martin, J1, 2, Autor                 
Affiliations:
1Department Protein Evolution, Max Planck Institute for Developmental Biology, Max Planck Society, ou_3375791              
2Protein Folding, Unfolding and Degradation Group, Department Protein Evolution, Max Planck Institute for Developmental Biology, Max Planck Society, ou_3477400              

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 Zusammenfassung: The AAA (ATPases associated with diverse cellular activities) protein family encompasses a large group of enzymes in all domains of life. AAA proteins assemble into oligomeric rings and undergo conformational changes during nucleotide hydrolysis cycles, exerted by highly conserved ATPase modules. These changes typically direct unfolding or remodeling of bound substrate proteins. The functional versatility of AAA proteins is primarily based on additional recognition domains that allow each family member to interact with a distinct set of substrates. As a consequence, AAA proteins can mediate diverse processes such as protein unfolding and degradation, vesicle transport, organelle assembly, and membrane dynamics.

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 Datum: 2021
 Publikationsstatus: Erschienen
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 Ort, Verlag, Ausgabe: -
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 Art der Begutachtung: -
 Identifikatoren: DOI: 10.1016/B978-0-12-819460-7.00065-7
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Titel: Encyclopedia of Biological Chemistry
Genre der Quelle: Buch
 Urheber:
Jez, J, Herausgeber
Affiliations:
-
Ort, Verlag, Ausgabe: San Diego, CA, USA : Elsevier, 3. ed.
Seiten: - Band / Heft: 1 Artikelnummer: - Start- / Endseite: 513 - 523 Identifikator: ISBN: 978-0-12-822040-5