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Abstract:
The specific functions of axons with growth cones might be correlated with a specific molecular composition differing from that of the perikarya. Thus axons with growth cones and cell perikaryal fractions were isolated by microdissection from neural retina explants of 6-day-old chick embryos. The protein composition of the minute amount of material available was analyzed with a two-dimensional micro-gel electrophoresis system in combination with various labeling procedures for surface- and glycoproteins. All methods showed, besides common features, proteins specific for axons with growth cones and for cell bodies.
