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  MODOMICS: a database of RNA modification pathways, update 2008

Czerwoniec, A., Dunin-Horkawicz, S., Purta, E., Kaminska, K., Kasprzak, J., Bujnicki, J., Grosjean, H., & Rother, K. (2009). MODOMICS: a database of RNA modification pathways, update 2008. Nucleic Acids Research (London), 37(Database issue), D118-D121. doi:10.1093/nar/gkn710.

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アイテムのパーマリンク: https://hdl.handle.net/21.11116/0000-000C-BEB1-6 版のパーマリンク: https://hdl.handle.net/21.11116/0000-000C-BEB2-5
資料種別: 学術論文

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 作成者:
Czerwoniec, A, 著者
Dunin-Horkawicz, S1, 著者                 
Purta, E, 著者
Kaminska, KH, 著者
Kasprzak, JM, 著者
Bujnicki, JM, 著者
Grosjean, H, 著者
Rother, K, 著者
所属:
1External Organizations, ou_persistent22              

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 要旨: MODOMICS, a database devoted to the systems biology of RNA modification, has been subjected to substantial improvements. It provides comprehensive information on the chemical structure of modified nucleosides, pathways of their biosynthesis, sequences of RNAs containing these modifications and RNA-modifying enzymes. MODOMICS also provides cross-references to other databases and to literature. In addition to the previously available manually curated tRNA sequences from a few model organisms, we have now included additional tRNAs and rRNAs, and all RNAs with 3D structures in the Nucleic Acid Database, in which modified nucleosides are present. In total, 3460 modified bases in RNA sequences of different organisms have been annotated. New RNA-modifying enzymes have been also added. The current collection of enzymes includes mainly proteins for the model organisms Escherichia coli and Saccharomyces cerevisiae, and is currently being expanded to include proteins from other organisms, in particular Archaea and Homo sapiens. For enzymes with known structures, links are provided to the corresponding Protein Data Bank entries, while for many others homology models have been created. Many new options for database searching and querying have been included. MODOMICS can be accessed at http://genesilico.pl/modomics.

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 日付: 2009-01
 出版の状態: 出版
 ページ: -
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 目次: -
 査読: -
 識別子(DOI, ISBNなど): DOI: 10.1093/nar/gkn710
PMID: 18854352
 学位: -

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出版物名: Nucleic Acids Research (London)
  その他 : Nucleic Acids Res
種別: 学術雑誌
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出版社, 出版地: Oxford : Oxford University Press
ページ: - 巻号: 37 (Database issue) 通巻号: - 開始・終了ページ: D118 - D121 識別子(ISBN, ISSN, DOIなど): ISSN: 0305-1048
CoNE: https://pure.mpg.de/cone/journals/resource/110992357379342