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  It is all in the noise: Efficient multi-task Gaussian process inference with structured residuals

Rakitsch, B., Lippert, C., Borgwardt, K., & Stegle, O. (2013). It is all in the noise: Efficient multi-task Gaussian process inference with structured residuals. Advances in Neural Information Processing Systems 26 (NIPS 2013), 1466-1474.

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Rakitsch, Barbara, Author
Lippert, Christoph, Author
Borgwardt, Karsten1, Author                 
Stegle, Oliver, Author
Affiliations:
1Department Molecular Biology, Max Planck Institute for Developmental Biology, Max Planck Society, ou_3375790              

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 Abstract: Multi-task prediction models are widely being used to couple regressors or classification models by sharing information across related tasks. A common pitfall of these models is that they assume that the output tasks are independent conditioned on the inputs. Here, we propose a multi-task Gaussian process approach to model both the relatedness between regressors as well as the task correlations in the residuals, in order to more accurately identify true sharing between regressors. The resulting Gaussian model has a covariance term that is the sum of Kronecker products, for which efficient parameter inference and out of sample prediction are feasible. On both synthetic examples and applications to phenotype prediction in genetics, we find substantial benefits of modeling structured noise compared to established alternatives.

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 Dates: 20132013
 Publication Status: Issued
 Pages: 1466-​1474
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Title: Advances in Neural Information Processing Systems 26 (NIPS 2013)
Source Genre: Journal
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Pages: - Volume / Issue: - Sequence Number: - Start / End Page: 1466 - 1474 Identifier: -