Synthetic genomics: a new venture to dissect genome fundamentals and engineer 
new functions

Schindler, Daniel; Dai, Junbiao; Cai, Yizhi

doi:10.1016/j.cbpa.2018.04.002

Local TagsRelease HistoryDetailsSummary

Synthetic genomics: a new venture to dissect genome fundamentals and engineer new functions

Schindler, D., Dai, J., & Cai, Y. (2018). Synthetic genomics: a new venture to dissect genome fundamentals and engineer new functions. CURRENT OPINION IN CHEMICAL BIOLOGY, 46, 56-62. doi:10.1016/j.cbpa.2018.04.002.

Item is Released

show all hide all

Basic

show hide

Item Permalink: https://hdl.handle.net/21.11116/0000-000D-078B-F Version Permalink: https://hdl.handle.net/21.11116/0000-000D-078C-E

Genre: Journal Article

Files

show Files

Locators

show

Creators

show

hide

Creators:
Schindler, Daniel¹, Author
Dai, Junbiao², Author
Cai, Yizhi², Author

Affiliations:
1Manchester Institute of Biotechnology, University of Manchester, UK, ou_persistent22
2external, ou_persistent22

Content

show

hide

Free keywords: -

Abstract: Since the first synthetic gene was synthesized in 1970s, the efficiency
and the capacity of made-to-order DNA sequence synthesis has increased
by several orders of magnitude. Advances in DNA synthesis and assembly
over the past years has resulted in a steep drop in price for custom
made DNA. Similar effects were observed in DNA sequencing technologies
which underpin DNA-reading projects. Today, synthetic DNA sequences with
more than 10 000 bps and turnaround times of a few weeks are
commercially available. This enables researchers to perform large-scale
projects to write synthetic chromosomes and characterize their
functionalities in vivo. Synthetic genomics opens up new paradigms to
study the genome fundamentals and engineer novel biological functions.

Details

show

hide

Language(s):

Dates: Date issued: 2018-10

Publication Status: Issued

Pages: -

Publishing info: -

Table of Contents: -

Rev. Type: -

Identifiers: ISI: 000449131300010
DOI: 10.1016/j.cbpa.2018.04.002

Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show

hide

Title: CURRENT OPINION IN CHEMICAL BIOLOGY

Source Genre: Journal

Creator(s):

Affiliations:

Publ. Info: -

Pages: - Volume / Issue: 46 Sequence Number: - Start / End Page: 56 - 62 Identifier: ISSN: 1367-5931