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  CD53 sends HSCs to sweet DREAMs

Karabacz, N., & Cabezas-Wallscheid, N. (2023). CD53 sends HSCs to sweet DREAMs. Blood, 141, 1100-1101. doi:10.1182/blood.2022019518.

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Item Permalink: https://hdl.handle.net/21.11116/0000-000D-0DED-B Version Permalink: https://hdl.handle.net/21.11116/0000-000D-0DEE-A
Genre: Journal Article

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10.1182_blood.2022019518.pdf (Publisher version), 423KB
 
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Restricted (Max Planck Institute of Immunobiology and Epigenetics, MFIB; )
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Copyright Date:
2023
Copyright Info:
The American Society of Hematology
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https://ashpublications.org/blood/article/141/10/1100/494778/CD53-sends-HSCs-to-sweet-DREAMs (Publisher version)
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 Creators:
Karabacz, Noémie1, Author
Cabezas-Wallscheid, Nina1, Author           
Affiliations:
1Department of Cellular and Molecular Immunology, Max Planck Institute of Immunobiology and Epigenetics, Max Planck Society, ou_2243641              

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 Abstract: In this issue of Blood, Greenberg et al1 show that hematopoietic stem cells (HSCs) employ a novel mechanism via promotion of the CD53-mediated dimerization partner, Rb-like, E2F and multi-vulval class B (DREAM) complex to return to quiescence after inflammatory and proliferative stress, thereby protecting them from functional decline.

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Language(s): eng - English
 Dates: 2023-03-09
 Publication Status: Published online
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1182/blood.2022019518
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Title: Blood
  Other : Blood
Source Genre: Journal
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Publ. Info: Washington, DC : American Society of Hematology
Pages: - Volume / Issue: 141 Sequence Number: - Start / End Page: 1100 - 1101 Identifier: ISSN: 0006-4971
CoNE: https://pure.mpg.de/cone/journals/resource/954925385125