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Abstract:
Quantitative CEST approaches can provide access to the exchange rate and solute concentration of exchange processes of interest. However, differences in the implementation of underlying Bloch-McConnell simulations will lead to differences in the determined quantitative parameters. Thus, we initiated a platform to compare and validate the CEST simulations from various CEST research groups. In this first comparison of continuous-wave saturation schemes, up to 5 different results for 8 compared simulations were observed. The project is still open for participation and we invite everbody to join the comparison and our planned discussions to finally realize a consensus on CEST simulations.
