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Next Generation Sequencing, Genome Comparison, Genomics, Bioinformatics, Speciation, Synteny analyses
Abstract:
Large amount of genome data are being generated by second- and now also third-generation sequencing technologies. The challenge no longer lies in the generation of the data, but in the analyses of it. We present an overview of approaches and methods to compare complete sequences of related fungal genomes. We focus on evolutionary analyses of genome alignments to describe species divergence and to identify footprints of demography and natural selection within and between species.