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Zusammenfassung:
Ralstonia pseudosolanacearum is a deadly bacterial plant pathogen known to infect many plant species. Comparative genomics of a South Korean population of R. pseudosolanacearum revealed that recombination frequently targets secreted gene products including type III secreted effectors and CdiA proteins, similar to hemagglutinin. CdiA proteins vary in the presence of a C-terminal toxin domain that inhibits the growth of adjacent cells lacking cognate immunity protein CdiI, a phenomenon called contact-dependent growth inhibition (CDI). CDI mediates both antagonistic and cooperative contact-dependent interactions, contributing to the formation of populations sharing identical CDI loci. R. pseudosolanacearum carries an expanded set of CDI loci compared to Burkholderia spp., where their function is better characterized. My work examines whether these loci mediate contact-dependent interactions and contribute to phenotypes associated with virulence and cooperative behavior in R. pseudosolanacearum.
