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  Protocol for making an animal model of “blindsight” in macaque monkeys

Takakuwa, N., Isa, K., Yamaguchi, R., Onoe, H., Takahashi, J., Yoshida, M., et al. (2022). Protocol for making an animal model of “blindsight” in macaque monkeys. STAR Protoc, 4(1): 101960. doi:10.1016/j.xpro.2022.101960.

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Item Permalink: https://hdl.handle.net/21.11116/0000-000D-DD9F-8 Version Permalink: https://hdl.handle.net/21.11116/0000-000D-DDA0-5
Genre: Journal Article

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Locator:
https://pubmed.ncbi.nlm.nih.gov/36566381/ (Any fulltext)
Description:
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OA-Status:
Gold

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 Creators:
Takakuwa , Norihiro1, 2, Author
Isa, Kaoru2, Author
Yamaguchi, Reona3, Author
Onoe, Hirotaka2, 4, Author
Takahashi, Jun5, Author
Yoshida, Masatoshi6, Author
Isa, Tadashi2, 3, 4, Author
Affiliations:
1Max Planck Institute for Brain Research, Max Planck Society, Max-von-Laue-Str. 4, 60438 Frankfurt am Main, DE, ou_2461692              
2Department of Neuroscience, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan, ou_persistent22              
3Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, Kyoto 606-8501, Japan., ou_persistent22              
4Human Brain Research Center, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan, ou_persistent22              
5Department of Clinical Application, Center for iPS Cell Research and Application, Kyoto University, Kyoto 606-8507, Japan, ou_persistent22              
6Center for Human Nature, Artificial Intelligence, and Neuroscience (CHAIN), Hokkaido University, Sapporo, Japan., ou_persistent22              

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Free keywords: Behavior; Cognitive Neuroscience; Microscopy; Model Organisms; Neuroscience.
 Abstract: Patients with damage to the primary visual cortex (V1) can respond correctly to visual stimuli in their lesion-affected visual field above the chance level, an ability named blindsight. Here, we present a protocol for making an animal model of blindsight in macaque monkeys. We describe the steps to perform pre-lesion training of monkeys on a visual task, followed by lesion surgery, post-lesion training, and evaluation of blindsight. This animal model can be used to investigate the source of visual awareness.

For complete details on the use and execution of this protocol, please refer to Yoshida et al. (2008) and Takakuwa et al. (2021).

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Language(s): eng - English
 Dates: 2022-12-23
 Publication Status: Issued
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.1016/j.xpro.2022.101960
PMID: 36566381
 Degree: -

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Title: STAR Protoc
Source Genre: Journal
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Publ. Info: Cambridge, MA ; Amsterdam : Cell Press ; Elsevier
Pages: - Volume / Issue: 4 (1) Sequence Number: 101960 Start / End Page: - Identifier: ISSN: 2666-1667
CoNE: https://pure.mpg.de/cone/journals/resource/2666-1667