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  Investigating secretion systems and effectors on Galleria mellonella

Habich, A., & Unterweger, D. (2024). Investigating secretion systems and effectors on Galleria mellonella. In L. Journet, & E. Cascales (Eds.), Bacterial Secretion Systems (2, pp. 601-608). New York, NY: (Humana) Springer US. doi:10.1007/978-1-0716-3445-5_38.

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Item Permalink: https://hdl.handle.net/21.11116/0000-000E-0615-4 Version Permalink: https://hdl.handle.net/21.11116/0000-000E-7BEF-C
Genre: Book Chapter

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978-1-0716-3445-5_38.pdf (Publisher version), 291KB
 
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 Creators:
Habich, Antonia1, 2, Author           
Unterweger, Daniel1, Author                 
Affiliations:
1Guest Group Infection Biology (Unterweger), Max Planck Institute for Evolutionary Biology, Max Planck Society, ou_3552274              
2IMPRS for Evolutionary Biology, Max Planck Institute for Evolutionary Biology, Max Planck Society, ou_1445639              

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 Abstract: Infection experiments with Galleria mellonella enable the measurement of virulence that is mediated by secretion systems and their effector proteins in vivo. G. mellonella has an innate immune system and shares similarities with the complex host environment of mammals. Unlike other invertebrate model systems, experiments can be performed at mammalian body temperature. Here, we describe the systemic infection of G. mellonella with Pseudomonas aeruginosa with and without functional secretion systems. A Kaplan–Meier curve is constructed showing the percent survival of animals over time.

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Language(s): eng - English
 Dates: 2023-11-072024
 Publication Status: Issued
 Pages: -
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 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.1007/978-1-0716-3445-5_38
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Project name : Grant
Grant ID : 01KI2020
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Funding organization : German Ministry of Education and Research

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Title: Bacterial Secretion Systems
  Subtitle : Methods and Protocols
Source Genre: Book
 Creator(s):
Journet, Laure1, Editor
Cascales, Eric1, Editor
Affiliations:
1 External Organizations, ou_persistent22            
Publ. Info: New York, NY : (Humana) Springer US, 2
Pages: XVI, 613 Volume / Issue: - Sequence Number: - Start / End Page: 601 - 608 Identifier: ISSN: 1064-3745
ISSN: 1940-6029
ISBN: 978-1-0716-3444-8
ISBN: 978-1-0716-3445-5

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Title: Methods in Molecular Biology
Source Genre: Series
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Publ. Info: New York, NY : (Humana) Springer US
Pages: - Volume / Issue: 2715 Sequence Number: - Start / End Page: - Identifier: ISSN: 1064-3745
ISSN: 1940-6029