非表示:
キーワード:
Adaptor Proteins, Signal Transducing, Antiviral Agents, Mitochondria, Mitochondrial Membranes, Mitochondrial Proteins
要旨:
Mitochondrial membrane remodeling has been linked with several cellular processes including mitochondrial damage or apoptotic cell death and proceeds via yet poorly understood mechanisms. In this issue of The FEBS Journal, Hwang et al. used different forms of super resolution microscopy to study the formation of macromolecular complexes of mitochondrial antiviral signal protein (MAVS). They found that dsRNA stimulation correlates with MAVS-dependent changes in the morphology of mitochondria that require MAVS transmembrane domain.
