Non-racemizing synthesis and stereoselective reduction of chiral α-amino ketones

Reetz, M. T.; Drewes, M. W.; Lennick, K.; Holdgrün, X.

doi:10.1016/0957-4166(90)90037-B

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Non-racemizing synthesis and stereoselective reduction of chiral α-amino ketones

Reetz, M. T., Drewes, M. W., Lennick, K., & Holdgrün, X. (1990). Non-racemizing synthesis and stereoselective reduction of chiral α-amino ketones. Tetrahedron: Asymmetry, 1(6), 375-378. doi:10.1016/0957-4166(90)90037-B.

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Item Permalink: https://hdl.handle.net/21.11116/0000-000E-7CC6-8 Version Permalink: https://hdl.handle.net/21.11116/0000-000E-7CC7-7

Genre: Journal Article

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Creators:
Reetz, M. T.¹, Author
Drewes, M. W.¹, Author
Lennick, K.¹, Author
Holdgrün, X.¹, Author

Affiliations:
1Philipps-Universität Marburg, Fachbereich Chemie, Hans-Meerwein-Straße, Marburg, ou_persistent22

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Abstract: α-Amino acids can be doubly benzylated at nitrogen, forming N,N-dibenzyl amino acids which can be converted into α-amino ketones 4 without appreciable racemization. The latter undergo stereoselective reduction with NaBH₄ under non-chelation control to form amino alkohols 5.

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Language(s): eng - English

Dates: Submitted: 1990-05-15Date issued: 1990

Publication Status: Issued

Pages: 4

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Rev. Type: Peer

Identifiers: DOI: 10.1016/0957-4166(90)90037-B

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Title: Tetrahedron: Asymmetry

Source Genre: Journal

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Publ. Info: Oxford : Pergamon

Pages: - Volume / Issue: 1 (6) Sequence Number: - Start / End Page: 375 - 378 Identifier: ISSN: 0957-4166
CoNE: https://pure.mpg.de/cone/journals/resource/954925577039