Multispecies Benchmark Analysis for LC-MS/MS Validation and Performance 
Evaluation in Bottom-Up Proteomics.

Jumel, Tobias; Shevchenko, Andrej

doi:10.1021/acs.jproteome.3c00531

Local TagsRelease HistoryDetailsSummary

Multispecies Benchmark Analysis for LC-MS/MS Validation and Performance Evaluation in Bottom-Up Proteomics.

Jumel, T., & Shevchenko, A. (2024). Multispecies Benchmark Analysis for LC-MS/MS Validation and Performance Evaluation in Bottom-Up Proteomics. Journal of proteome research, 23(2), 684-691. doi:10.1021/acs.jproteome.3c00531.

Item is Released

show all hide all

Basic

show hide

Item Permalink: https://hdl.handle.net/21.11116/0000-000F-15E4-8 Version Permalink: https://hdl.handle.net/21.11116/0000-000F-15E5-7

Genre: Journal Article

Files

show Files

Locators

show

Creators

show

hide

Creators:
Jumel, Tobias, Author
Shevchenko, Andrej¹, Author

Affiliations:
1Max Planck Institute for Molecular Cell Biology and Genetics, Max Planck Society, ou_2340692

Content

show

hide

Free keywords: -

Abstract: We present an instrument-independent benchmark procedure and software (LFQ_bout) for the validation and comparative evaluation of the performance of LC-MS/MS and data processing workflows in bottom-up proteomics. The procedure enables a back-to-back comparison of common and emerging workflows, e.g., diaPASEF or ScanningSWATH, and evaluates the impact of arbitrary and inadequately documented settings or black-box data processing algorithms. It enhances the overall performance and quantification accuracy by recognizing and reporting common quantification errors.

Details

show

hide

Language(s):

Dates: Date issued: 2024-02-02

Publication Status: Issued

Pages: -

Publishing info: -

Table of Contents: -

Rev. Type: -

Identifiers: DOI: 10.1021/acs.jproteome.3c00531
Other: cbg-8654
PMID: 38243904

Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show

hide

Title: Journal of proteome research

Other : J Proteome Res

Source Genre: Journal

Creator(s):

Affiliations:

Publ. Info: -

Pages: - Volume / Issue: 23 (2) Sequence Number: - Start / End Page: 684 - 691 Identifier: -