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  In vivo high-field MR spectroscopy: from systems architecture to application

Kempf, N., Pravdivtsev, A., Plaumann, M., Körber, R., Engelmann, J., Neumann, R., et al. (2024). In vivo high-field MR spectroscopy: from systems architecture to application. Poster presented at 65th Experimental Nuclear Magnetic Resonance Conference (ENC 2024), Pacific Grove, CA, USA.

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Datensatz-Permalink: https://hdl.handle.net/21.11116/0000-000F-232A-B Versions-Permalink: https://hdl.handle.net/21.11116/0000-000F-232D-8
Genre: Poster

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 Urheber:
Kempf, N1, Autor                 
Pravdivtsev, AN, Autor
Plaumann, M, Autor
Körber , R, Autor
Engelmann, J1, Autor           
Neumann, R1, Autor           
Bullinger, F1, Autor           
Scheffler, K1, Autor                 
Theis, T, Autor
Buckenmaier, K1, Autor                 
Affiliations:
1Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497796              

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 Zusammenfassung: The zero and ultra-low field regime opens up new opportunities for NMR by parahydrogen-based hyperpolarization. Our in situ combination of SABRE with a SQUID between 10 fT and 30 mT embodies a highly versatile magnetic resonance system. Recent efforts have improved 15N polarization by 30 % with alt-SABRE- SHEATH and polarized [1-13C]pyruvate in situ with LIGHT-SABRE continuously without magnetic field cycling. We obtained 3- dimensional 13C images of [1-13C]pyruvate in a phantom with sub- millimeter resolution at 120 μT. Using a SABRE-SHEATH ZULF sequence we measured the hyperpolarized signals of [1-13C]pyruvate between 1 nT and 100 μT, showing the transition between the Zeeman dominated and the J-coupling dominated regime. The results pave the way for in vivo ULF imaging with SABRE.

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 Datum: 2024-04
 Publikationsstatus: Online veröffentlicht
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Veranstaltung

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Titel: 65th Experimental Nuclear Magnetic Resonance Conference (ENC 2024)
Veranstaltungsort: Pacific Grove, CA, USA
Start-/Enddatum: 2024-04-07 - 2024-04-11

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Titel: 65th Experimental Nuclear Magnetic Resonance Conference (ENC 2024)
Genre der Quelle: Konferenzband
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Affiliations:
Ort, Verlag, Ausgabe: -
Seiten: - Band / Heft: - Artikelnummer: 108 Start- / Endseite: 61 Identifikator: -