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Abstract:
Motivation: The inherently slow MRI scans can be accelerated through rapid modulation of nonlinear gradient fields; however, its fundamental mechanisms and limits remain incompletely understood and validated.
Goal(s): We investigate accelerated MRI with flexible modulations of nonlinear B0 fields using a custom-built local B0 array.
Approach: The sampling theory is extended to rigorously compare nonlinear field modulation schemes in a quantitative k-space. A novel field calibration technique is proposed to enhance reconstruction. With safety evaluations, we perform in-vivo accelerated scans.
Results: Our in-vivo 2D FLASH scans make significant steps to speed up MRI with local B0 array, achieving eight-fold joint acceleration with parallel imaging.
Impact: For the first time, the sampling efficiency of nonlinear gradients in the entire k-space is quantitatively visualized, allowing rigorous comparison of distinct B0 modulations. Furthermore, the field estimation technique enables fast and robust in-vivo scans accelerated by flexible nonlinear fields.
