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  Navigator-free multi-shot EPI with shift-invariant kernel extraction in subspace

Tian, R., Uecker, M., & Scheffler, K. (2024). Navigator-free multi-shot EPI with shift-invariant kernel extraction in subspace. Poster presented at ISMRM & ISMRT Annual Meeting & Exhibition 2024, Singapore.

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Tian, R1, Author                 
Uecker, M, Author
Scheffler, K1, Author                 
Affiliations:
1Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497796              

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 Abstract: Motivation: In functional and diffusion MRI, multi-shot EPI enhances spatial resolution and minimizes distortion compared to single-shot scans. However, its vulnerability to shot-to-shot phase variations presents a significant challenge, with various proposed methods having drawbacks. Goal(s): We propose a robust, navigator-free, computational efficient multi-shot method without SNR penalty. Approach: In readout-segmented multi-shot EPI, we exploit the k-space overlapped regions between adjacent segments to extract relative phase fluctuations. This method, inspired by ESPIRiT and nonlinear gradient calibration, efficiently extracts shot-dependent phase variations in subspace. Results: Our ex-vivo and in-vivo scans, including diffusion-weighted imaging, successfully achieves a high in-plane resolution of about 0.6mm without ghost artifacts. Impact: Our proposed multi-shot technique eliminates the needs for time-consuming navigators, provides robust high-resolution diffusion and potentially functional imaging, and could be easily adapted for interleaved Cartesian and spiral EPI allowing robust phase error estimation from merely small k-space regions.

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 Dates: 2024-05
 Publication Status: Published online
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Title: ISMRM & ISMRT Annual Meeting & Exhibition 2024
Place of Event: Singapore
Start-/End Date: 2024-05-04 - 2024-05-09

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Title: ISMRM & ISMRT Annual Meeting & Exhibition 2024
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 1081 Start / End Page: 586 Identifier: -