English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
 
 
DownloadE-Mail
 DetailsSummary
  Nonlinear dynamics of femtosecond laser interaction with the central nervous system in zebrafish

Jun, S., Herbst, A., Scheffter, K., John, N., Kolb, J., Wehner, D., et al. (2024). Nonlinear dynamics of femtosecond laser interaction with the central nervous system in zebrafish. Communications Physics, (7): 161. doi:10.1038/s42005-024-01653-2.

Item is

 

show all hide all

Basic

show hide
Item Permalink: https://hdl.handle.net/21.11116/0000-000F-4F6C-1 Version Permalink: https://hdl.handle.net/21.11116/0000-000F-4F6D-0
Genre: Journal Article

Files

show Files
hide Files
:
s42005-024-01653-2.pdf (Publisher version), 3MB
View   Save
File Permalink:
https://hdl.handle.net/21.11116/0000-000F-4F6E-F
Name:
s42005-024-01653-2.pdf
Description:
-
OA-Status:
Not specified
Visibility:
Public
MIME-Type / Checksum:
application/pdf / [MD5]
Technical Metadata:
View
Copyright Date:
-
Copyright Info:
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
License:
http://creativecommons.org/licenses/by/4.0/

Locators

show

Creators

show
hide
 Creators:
Jun, Soyeon1, 2, Author           
Herbst, Andreas1, 2, Author           
Scheffter, Kilian1, 2, Author           
John, Nora2, 3, 4, Author           
Kolb, Julia2, 3, 4, Author           
Wehner, Daniel2, 3, 4, Author           
Fattahi, Hanieh1, 2, Author           
Affiliations:
1Fattahi Research Group, Research Groups, Max Planck Institute for the Science of Light, Max Planck Society, ou_3215430              
2Friedrich-Alexander-Universität Erlangen-Nürnberg, External Organizations, DE, ou_3487833              
3Wehner Research Group, Guck Division, Max Planck Institute for the Science of Light, Max Planck Society, ou_3358768              
4Max-Planck-Zentrum für Physik und Medizin, Max Planck Institute for the Science of Light, Max Planck Society, ou_3164414              

Content

show
hide
Free keywords: -
 Abstract: Understanding the photodamage mechanism underlying the highly nonlinear dynamic of femtosecond laser pulses at the second transparent window of tissue is crucial for label-free microscopy. Here, we report the identification of two cavitation regimes from 1030 nm pulses when interacting with the central nervous system in zebrafish. We show that at low repetition rates, the damage is confined due to plasma-based ablation and sudden local temperature rise. At high repetition rates, the damage becomes collateral due to plasma-mediated photochemistry. Furthermore, we investigate the role of fluorescence labels with linear and nonlinear absorption pathways in optical breakdown. To verify our findings, we examined cell death and cellular responses to tissue damage, including the recruitment of fibroblasts and immune cells after irradiation. These findings contribute to advancing the emerging nonlinear optical microscopy techniques and provide a strategy for inducing precise, and localized injuries using near-infrared femtosecond laser pulses.

Details

show
hide
Language(s): eng - English
 Dates: 2024-05-21
 Publication Status: Issued
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.1038/s42005-024-01653-2
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Communications Physics
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: London : Nature Publishing Group
Pages: - Volume / Issue: (7) Sequence Number: 161 Start / End Page: - Identifier: ISSN: 2399-3650
CoNE: https://pure.mpg.de/cone/journals/resource/2399-3650