ausblenden:
Schlagwörter:
methylation; late-stage functionalization; aryl thianthrenium salt; Catellani reaction; C-H activation
Zusammenfassung:
Here we report the reaction of aryl thianthrenium salts that allows selective functionalization of the meta position of arenes. The combination of a site-selective thianthrenation with a Catellani reaction provides access to 3,5-dimethylated arenes. The developed reaction is complementary to the previously discovered reductive ipso-alkylation of aryl thianthrenium salts and extends the possibilities for late-stage methylation of arenes with a single aryl thianthrenium salt.
