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  Localization and Characterization of Odor Receptors in C. elegans

DiBianca, I., Quiogue, A., Ghaffan, C., Stayer-Wilburn, O., Thakker, V., Harwood, M., et al. (2018). Localization and Characterization of Odor Receptors in C. elegans. Poster presented at C. elegans Neuronal Development, Synaptic Function & Behavior Topic Meeting 2018, Madison, WI, USA.

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Item Permalink: https://hdl.handle.net/21.11116/0000-0010-59D6-9 Version Permalink: https://hdl.handle.net/21.11116/0000-0010-59D8-7
Genre: Poster

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https://invivobiosystems.com/wp-content/uploads/2018/06/2018NeuroMeetingBook.pdf (Abstract)
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 Creators:
DiBianca, I, Author
Quiogue, A, Author
Ghaffan, C, Author
Stayer-Wilburn, O, Author
Thakker, V, Author
Harwood, M, Author
Maher, S, Author
Resch, L, Author
Nathan, S, Author
Dalton, C, Author
Cox-Harris, A, Author
Morton, R, Author
Jerome, E, Author
Mankins, W, Author
Daffeh, L, Author
Tirumalasetty, K, Author
Szentkuti, H, Author
Sullivan, J, Author
Hernandez, G, Author
Fekrinia, K, Author
more..
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1External Organizations, ou_persistent22              

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 Abstract: Caenorhabditis elegans uses a small number of sensory neurons to respond to a wide variety of odors. The identities of the odor receptors and the stimuli to which they respond are largely unknown. We are working toward localizing odor receptors and pairing them with the odors they sense, with a focus on AWC-expressed receptors. We are localizing candidate odor receptor proteins using traditional and signal-enhanced translational GFP reporters. We are also generating novel odor receptor gene knockouts using CRISPR, which we are testing in chemotaxis assays for odor response behavior. By helping to illuminate the organization and function of olfactory receptors, we hope to enrich our understanding of the C. elegans olfactory system, and the strategies it uses to interpret information.

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 Dates: 2018-06
 Publication Status: Published online
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Title: C. elegans Neuronal Development, Synaptic Function & Behavior Topic Meeting 2018
Place of Event: Madison, WI, USA
Start-/End Date: 2018-06-25 - 2018-06-28

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Title: C. elegans Neuronal Development, Synaptic Function & Behavior Topic Meeting 2018
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: - Start / End Page: 216 Identifier: -