The future of genome-based medicine

Morris, Q; Brenner, SE; Listgarten, J; Stegle, O

Local TagsRelease HistoryDetailsSummary

The future of genome-based medicine

Morris, Q., Brenner, S., Listgarten, J., & Stegle, O. (2013). The future of genome-based medicine. In R. Altman, A. Dunker, L. Hunter, T. Murray, & T. Klein (Eds.), Biocomputing 2013: Pacific Symposium on Biocomputing (pp. 456-458). Singapore: World Scientific Publishing Company.

Item is Released

show all hide all

Basic

show hide

Item Permalink: https://hdl.handle.net/21.11116/0000-0010-5B04-4 Version Permalink: https://hdl.handle.net/21.11116/0000-0010-5B05-3

Genre: Conference Paper

Files

show Files

Locators

show

Creators

show

hide

Creators:
Morris, Q, Author
Brenner, SE, Author
Listgarten, J, Author
Stegle, O¹, Author

Affiliations:
1Department Molecular Biology, Max Planck Institute for Developmental Biology, Max Planck Society, ou_3375790

Content

show

hide

Free keywords: -

Abstract: There has been unprecedented public investment in sequencing human and cancer genomes in the hopes of understanding disease [1, 2]. At the same time, large genome-wide association studies have helped elucidating the genetic underpinning of common diseases, identifying thousands of putative disease relevant loci [7, 8]. Complementary molecular profiling studies have revealed that several of these loci are co-associated with individual mRNA levels, suggesting candidate pathways that are putative mediators of genetic signals [7]. Coupled with the public investment, there is considerable personal investment in genetic profiling, being offered by companies such as 23andMe, deCODEme and others. Although this work has led to amazing discoveries, such as the surprising genetic, subclonal diversity within tumor populations (e.g., [3–5]), it’s not clear how much how these insights will improve personalization of medicine.

Details

show

hide

Language(s):

Dates: Date issued: 2013

Publication Status: Issued

Pages: -

Publishing info: -

Table of Contents: -

Rev. Type: -

Identifiers: PMID: 23424151

Degree: -

Event

show

hide

Title: Pacific Symposium on Biocomputing (PSB 2013)

Place of Event: Kohala Coast, HI, USA

Start-/End Date: 2013-01-03 - 2013-01-07

Legal Case

show

Project information

show

Source 1

show

hide

Title: Biocomputing 2013: Pacific Symposium on Biocomputing

Source Genre: Proceedings

Creator(s):
Altman, RB, Editor
Dunker, AK, Editor
Hunter, L, Editor
Murray, T, Editor
Klein, TE, Editor

Affiliations:
-

Publ. Info: Singapore : World Scientific Publishing Company

Pages: - Volume / Issue: - Sequence Number: - Start / End Page: 456 - 458 Identifier: ISBN: 978-981-4596-36-7