ausblenden:
Schlagwörter:
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Zusammenfassung:
Small RNAs including microRNAs (miRNAs) are potent agents of gene and genome regulation, but we are only beginning to understand how they discriminate between different potential targets, and how they affect different biological pathways. I will present three topics relating to this question. I will begin by discussing how we discovered two years ago the first plant miRNA mutant. Next, I will describe the use of transcript profiling to identify miRNA targets, including the possibility of off-target effects. In addition, I will present studies on the signaling pathways controlled by one of the miRNAs, miR319. If time permits, I will also briefly discuss insights into plant miRNA evolution.
