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Abstract:
MRI of human ex vivo tissue can be of value for pushing MRI resolution limits and for validation based on histology [1,2] and lCT3 of the same specimens. MRI at 9.4T in vivo is compatible with whole brain ex vivo MRI, revealing absence of significant variation in cortical thickness and maintained QSM sen- sitivity to expected iron concentrations [4]. To further our understanding of these observations, we extended the previous com- parison to include R2 and R2’ mappings and qMRI at 3T, where the contributions from different relaxation mechanisms are different than at 9.4T.