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  The arduous way to the egg: Follow the nose

Bartram, S., & Boland, W. (2003). The arduous way to the egg: Follow the nose. Angewandte Chemie, International Edition in English, 42(39), 4729-4731. doi:10.1002/anie.200301676.

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Bartram, S.1, Author              
Boland, W.1, Author              
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1Department of Bioorganic Chemistry, MPI for Chemical Ecology, Max Planck Society, ou_24028              

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Free keywords: bourgeonal, chemotaxis, odorants, receptors, signal cascades sperm chemotaxis; receptors; odorant; cells
 Abstract: The scent of success! On their way to the ovum, human sperms are guided by chemical signals, which may be related to the scent of the lily of the valley. para‐Substituted 3‐phenylpropanals such as cyclamal and bourgeonal are recognized by an olfactory receptor of the sperm and trigger an influx of Ca2+ ions via cAMP as a second messenger. The signal modulates the swimming behavior and speed of the sperm. Undecanal acts as an antagonist and makes the sperm cells slow and disorientated.

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 Dates: 2003
 Publication Status: Published in print
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 Identifiers: Other: BOL136
DOI: 10.1002/anie.200301676
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Title: Angewandte Chemie, International Edition in English
  Other : Angewandte Chemie International Edition in English
  Other : Angew. Chem. Int. Ed. Engl.
Source Genre: Journal
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Publ. Info: Weinheim : Wiley-VCH
Pages: - Volume / Issue: 42 (39) Sequence Number: - Start / End Page: 4729 - 4731 Identifier: ISSN: 0570-0833
CoNE: https://pure.mpg.de/cone/journals/resource/0570-0833