非表示:
キーワード:
aldehydes; lipids; lipoproteins; oxygenations
Lipid oxidation-products; unsaturated fatty-acids; autoxidation; aldehydes; fibroblasts; cells
要旨:
The oxidation of low‐density lipoprotein (LDL) in vitro was studied by a combination of solid‐phase microextraction and GC/MS. 2‐trans,4‐cis‐2,4‐Decadienal, which is strongly toxic in vitro, was detected as the early oxidation product. This compound is degraded further to hexanal and (by cyclization of 4‐hydroxy‐2‐nonenal) to 2‐pentylfuran.
